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05/16/2013 3:36 AM ET

San Diego native Strasburg ready for Petco Park debut

LOS ANGELES -- Nationals right-hander Stephen Strasburg is scheduled to start against the Padres in San Diego on Friday. It will mark the first time Strasburg will pitch in his hometown as a Major Leaguer.

According to manager Davey Johnson, Strasburg will be driving to San Diego to be with his family. Johnson doesn't expect any distractions on Strasburg's end.

"It's always good to be in your hometown. Everybody likes to do that," Johnson said. "He is doing well, we just haven't scored him many runs. If we score him some runs, then he will be fine."

Strasburg hasn't won a game since Opening Day against the Marlins, but he has a respectable 3.10 ERA.

Detwiler, Ramos injured against Dodgers

LOS ANGELES -- Nationals left-hander Ross Detwiler and catcher Wilson Ramos left Wednesday night's 3-1 loss to the Dodgers because of injuries.

Detwiler sustained tightness in his lower back in the top the third inning, during a sacrifice bunt that advanced Roger Bernadina to second base. Detwiler had problems running the bases. His back would get worse in the bottom of the inning.

It was believed that Detwiler hurt his back while catching a wide throw from shortstop Ian Desmond in the bottom of the third, but Detwiler said he felt fine.

Detwiler had problems throwing pitches after that, and pitching coach Steve McCatty, head athletic trainer Lee Kuntz and manager Davey Johnson came to his aid. Detwiler stayed in and allowed a single to A.J. Ellis and walked Ethier to load the bases. Detwiler got out of the inning when Scott Van Slyke lined out to third baseman Ryan Zimmerman. Detwiler was then replaced by Craig Stammen, who pitched three shutout innings and struck out three batters.

It's not known if Detwiler will make his next start in San Francisco next week.

"It's not all that great now. Hopefully, tomorrow morning it will feel a lot better," Detwiler said.

An inning later, catcher Wilson Ramos re-injured his left hamstring, the same injury that put him on the disabled list last month. Ramos hit a two-out single to left field and ran gingerly to first. Once he reached the bag, he slammed his helmet to the ground and was replaced by Kurt Suzuki. Ramos felt something was wrong when he doubled in the second inning. Manager Davey Johnson believes Ramos will go on the DL.

"I'm not too hurt, but I talked to Lee and told him that I don't want to be hurt again, so they took me out of the game. I don't want to be on the DL again," Ramos said. "But it's a little bit sore. ... I was working hard with my hamstring and trying to get my hamstring stronger. But I don't know what happened today. I was feeling good before I felt it today."

Sore Harper hopes to start on Thursday

LOS ANGELES -- Nationals outfielder Bryce Harper was limited to a pinch-hit appearance in Wednesday night's 3-1 loss to the Dodgers because he was still sore in the wake of Monday's collision with the right-field wall at Dodger Stadium.

Harper was called on with a runner on second and one out in the ninth inning and grounded out to first base.

Asked how he felt after the game, Harper said, "Terrible."

Harper said the biggest issue he is dealing with is his abdomen. He also had rib cage and knee soreness.

Before the game, Harper was able to do running drills and take batting practice. He wasn't having any problems swinging the bat. In fact, several balls were hit over the fence.

Harper hurt himself in the fifth inning against the Dodgers on Monday night. The Nationals were leading, 6-0, when A.J. Ellis hit a leadoff fly ball to right field. Harper, 20, thought he had more room to make the play, but Harper crashed into the wall face-first and was shaken up on the play. Ellis ended up with a triple.

Harper would leave the game and was nauseous the next day. Johnson is hoping that Harper can start Thursday when the Nationals open a four-game series against the Padres in San Diego.

"He is going to be fine. I wasn't worried about the concussion. He got hit in the chin," Johnson said before Wednesday's game. "He has some aches and pain, but he is young. He will probably be all right today."

Bill Ladson is a reporter for MLB.com and writes an MLBlog, All Nats All the time. He also could be found on Twitter @WashingNats. This story was not subject to the approval of Major League Baseball or its clubs.