Marlins starter Chris Volstad, who will take the hill opposite Strasburg, will share the honor, too.
The duo will be the last two pitchers to start a big league game at Sun Life Stadium. The Florida Marlins will move into a new stadium next season and will be known as the Miami Marlins.
"That's pretty good to have that honor," Volstad said. "Just to be with the guys here right now and the past players that are going to be coming and be a part of it. To have that and be remembered with the organization is cool."
Volstad, a South Florida native, has four consecutive no-decisions and has not won since July 10. However, he has consecutive outings of seven innings pitched.
He's 3-7 with a 5.04 ERA at home this season.
Strasburg found himself in trouble in the first inning against the Braves in his last start, throwing 38 pitches and allowing three runs -- two earned. He settled down and retired nine out of the last 10 hitters he faced in the four-inning outing. On a pitch count, Strasburg tossed 76 of the 80 pitches he was schedule to throw.
"He really started to overthrow and not pitch," manager Davey Johnson said. "He got into a little trouble stepping back. He just got pumped up. He was just throwing the ball and not pitching. It was pretty obvious. ... He just quite couldn't get it under control, he was too hyped up."
Strasburg said he wasn't uncomfortable on the mound.
"I left some pitches up," Strasburg said. "If I got the ball down, there would have been ground balls, but they put it in play. They got the job done."
Nationals: Espinosa sets rookie home-run mark
Danny Espinosa set a club record for home runs by a rookie with 21 this season. He's just the third rookie second baseman in Major League history with at least 20 home runs. Atlanta's Dan Uggla hit 27 home runs for the Marlins in 2006 and White Sox infielder Alexei Ramirez hit 21 home runs in 2008.
This year's club is the first team from D.C. to place third or higher in the standings since the 1945 Nationals placed second in the American League, 1 1/2 games behind pennant-winning Detroit.Marlins: Bonaficio putting up big numbers
Emilio Bonifacio has notched career highs with 26 doubles and 40 stolen bases this season. He is just the third player in club history with at least 25 doubles and 40 stolen bases in a season.
The South Florida Chapter of the Baseball Writers Association of America announced their 2011 award winners. Mike Stanton was named Most Valuable Player, Bonifacio earned the Jeff Conine "Mr. Marlin" Award, Steve Cishek was named Rookie of the Year and John Buck earned the Charlie Hough "Good Guy" Award.
Since 1996, only two players age 21 or under have hit more home runs in a single season than Mike Stanton, who has 34 homers this year. Albert Pujols hit 37 as a 21-year old in 2001, and Alex Rodriguez hit 36 as a 20-year old in 1996.
Marlins manager Jack McKeon, who now has 281 wins, will step down following Wednesday's game with the most wins as a manager in Marlins history.
There will be a postgame ceremony with former Marlins players and the unveiling of the fans' vote for the top 10 moments in team history following tomorrow's game. Gates open at 2 p.m. ET, and tickets to the upper deck will be sold.